Recent years have seen significant evolution in the treatment of PBC. Furthermore, the importance of health-related quality of life (HRQoL) is widely appreciated, and approaches to the management of the symptoms contributing to HRQoL, most notably pruritus, continues to improve. HRQoL provides insights into how patients perceive their own disease processes, which understandably may be different from the way they are perceived by clinicians. The current guideline recommends that clinicians should screen for PBC symptoms on an annual basis.

The PBC-10 is a rigorously developed, valid, simple and short measure, that can be easily used for assessing the HRQL in patients with PBC in clinical practice


PBC-10 questionnaire (Blank version)


Alrubaiy L, Mells G, Flack S, Bosomworth H, Hutchings H, Williams J, Jones D; UK-PBC Research Consortium. PBC-10: a short quality of life measure for clinical screening in primary biliary cholangitis. Aliment Pharmacol Ther. 2019 Dec;50(11-12):1223-1231