UK-PBC Risk Calculator

The UK-PBC Risk Score Calculator is now available on our website. The link is provided below.

The calculator uses information from the UK-PBC Research Cohort to estimate the risk (expressed in percentage) that a PBC patient established on treatment with Ursodeoxycholic acid (UDCA) will develop liver failure requiring liver transplantation within 5, 10 or 15 years from diagnosis.

The score may be used to identify high-risk patients for closer monitoring and second-line therapies, as well as low-risk patients who could potentially be followed-up in primary care.

To use the UK-PBC Risk Score calculator, enter the laboratory test measurements and upper limits of normal (ULN) for the total bilirubin (BIL12); alanine transaminase or aspartate transaminase (TA12), and alkaline phosphatase (ALP12) after at least 12 months of UDCA, and the laboratory test measurements and lower limits of normal (LLN) for the serum albumin and platelet count in the same timeframe.

Click here to access the calculator.